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Evaluation of Alum-Naltrexone Adjuvant Activity, on Efficacy of Anti-Leishmania Immunization with Autoclaved Leishmania major (MRHO/IR/75/ER) Antigens in BALB/C Mice

BACKGROUND: Naltrexone, an opioid receptor antagonist shifts the immune response toward a Th1 profile. In the current study, we evaluated the efficacy of the mixture of NTX and alum, as a new adjuvant, to enhance immune response and induce protection against Leishmania major in a mouse model. METHOD...

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Detalles Bibliográficos
Autores principales:	MOHAMMADZADEH HAJIPIRLOO, Habib, BOZORGOMD, Arezoo, SHAHABI, Shahram, HAZRATI TAPPEH, Khosrow, KARAMATI, Seyed Ahmad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316561/ https://www.ncbi.nlm.nih.gov/pubmed/25678914

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