Cargando…

Evaluation of Alum-Naltrexone Adjuvant Activity, on Efficacy of Anti-Leishmania Immunization with Autoclaved Leishmania major (MRHO/IR/75/ER) Antigens in BALB/C Mice

BACKGROUND: Naltrexone, an opioid receptor antagonist shifts the immune response toward a Th1 profile. In the current study, we evaluated the efficacy of the mixture of NTX and alum, as a new adjuvant, to enhance immune response and induce protection against Leishmania major in a mouse model. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales:	MOHAMMADZADEH HAJIPIRLOO, Habib, BOZORGOMD, Arezoo, SHAHABI, Shahram, HAZRATI TAPPEH, Khosrow, KARAMATI, Seyed Ahmad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Tehran University of Medical Sciences 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316561/ https://www.ncbi.nlm.nih.gov/pubmed/25678914

Ejemplares similares

Peganum harmala Aqueous and Ethanol Extracts Effects on Lesions Caused by Leishmania major (MRHO/IR/75/ER) in BALB/c Mice
por: Khoshzaban, Fariba, et al.
Publicado: (2014)

Induction of Oxidative Stress in Skin and Lung of Infected BALB/C Mice with Iranian Strain of Leishmania major (MRHO/IR/75/ER)
por: JAFARI, Mahvash, et al.
Publicado: (2014)

P-glycoprotein A Gene Expression in Glucantime-Resistant and Sensitive Leishmania major (MRHO/IR/75/ER)
por: SOLEIMANIFARD, Simindokht, et al.
Publicado: (2014)

Effect of trinitroglycerin therapy on serum zinc and copper levels and liver enzyme activities in BALB/c mice infected with Leishmania major MRHO/IR/75/ER
por: Najafzade, Mana, et al.
Publicado: (2015)

The Effect of Aqueous Garlic Extract on Interleukin-12 and 10 Levels in Leishmania major (MRHO/IR/75/ER) Infected Macrophages
por: Gharavi, MJ, et al.
Publicado: (2011)

In Vitro Study on Cytotoxic Effects of ZnO Nanoparticles on Promastigote and Amastigote Forms of Leishmania major (MRHO/IR/75/ER)
por: DELAVARI, Mahdi, et al.
Publicado: (2014)

Antileishmanial Activity of Lavandula angustifolia and Rosmarinus Officinalis Essential Oils and Nano-emulsions on Leishmania major (MRHO/IR/75/ER)
por: SHOKRI, Azar, et al.
Publicado: (2017)

Molecular Characterization of Aquaglyceroporine: A Novel Mutation in LmAQP1 from Leishmania major (MRHO/IR/75/ER)
por: ESLAMI, Gilda, et al.
Publicado: (2019)

MicroRNAs Expression Induces Apoptosis of Macrophages in Response to Leishmania major (MRHO/IR/75/ER): An In-Vitro and In-Vivo Study
por: GHOLAMREZAEI, Mostafa, et al.
Publicado: (2020)

In Vitro Study of the Leishmanicidal Activity of Perovskia Abrotanoides Terpenoid-Rich Fractions Against Leishmania Major (MRHO/IR/75/ER)
por: Dinani, Masoud Sadeghi, et al.
Publicado: (2023)

Therapeutic Effect of Scrophularia striata Ethanolic Extract against Localized Cutaneous Leishmaniasis Caused by Leishmania major (MRHO/IR/75/ER)
por: ZAHIRI, Malihe, et al.
Publicado: (2016)

Comparison of p27 Gene Expression of Promastigote and Amastigote Forms of Leishmania major (MRHO/IR/75/ER) by Real-time RT-PCR
por: ELIKAEE, Samira, et al.
Publicado: (2018)

Host-parasite Responses Outcome Regulate the Expression of Antimicrobial Peptide Genes in the Skin of BALB/c and C57BL/6 Murine Strains Following Leishmania major MRHO/IR/75/ER Infection
por: DANESHVAR, Hamid, et al.
Publicado: (2018)

Evaluation of Cellular Immune Responses in Dogs Immunized with Alum-Precipitated Autoclaved Leishmania major along with BCG and Imiquimod
por: Barati, Mohammad, et al.
Publicado: (2021)

Designing and Cloning Molecular Constructs to Knock Out N-Acetylglucosamine Phosphatidylinositol De-N-Acetylase (GPI12) Gene in Leishmania major (MRHO/IR/75/ER)
por: GHASEMI NEJAD ALMANI, Pooya, et al.
Publicado: (2016)

Evaluation of Adjuvant Effectiveness of Alum-Propranolol Mixture on the Immunogenicity of Excreted/Secreted Antigens of Toxoplasma gondii RH Strain
por: Meshkini, Elyar, et al.
Publicado: (2021)

Double-Blind Randomized Efficacy Field Trial of Alum Precipitated Autoclaved Leishmania major (Alum-ALM) Vaccine Mixed With BCG Plus Imiquimod Vs. Placebo Control Group
por: BARATI, Mohammad, et al.
Publicado: (2015)

Fe3O4@Bio-MOF Nanoparticles Combined with Artemisinin, Glucantime®, or Shark Cartilage Extract on Iranian Strain of Leishmania major (MRHO/IR/75/ER): An In-Vitro and In-Vivo Study
por: GHAFARIFAR, Fatemeh, et al.
Publicado: (2020)

Human Cystic Echinococcosis in West Azerbaijan, Northwest Iran: A Retrospective Hospital Based Survey from 2000 To 2009
por: Hajipirloo, H Mohammadzadeh, et al.
Publicado: (2013)

Evaluation of Immunogenic Effect of Toxoplasma gondii Recombinant SAG-1 Antigen with Propranolol as Adjuvant in BALB/c Mice
por: Abasi, Esmaeil, et al.
Publicado: (2019)

Synthesis and Comparison of In Vitro Leishmanicidal Activity of 5-(Nitroheteroaryl)-1,3,4-Thiadiazols Containing Cyclic Amine of Piperidin-4-ol at C-2 with Acyclic Amine Analogues against Iranian Strain of Leishmania major (MRHO/IR/75/ER)
por: Tahghighi, Azar, et al.
Publicado: (2017)

Identification of Echinococcus granulosus Strains in Isolated Hydatid Cyst Specimens from Animals by PCR-RFLP Method in West Azerbaijan – Iran
por: HANIFIAN, Haleh, et al.
Publicado: (2013)

Biodistribution of meglumine antimoniate in healthy and Leishmania (Leishmania) infantum chagasi-infected BALB/c mice
por: Borborema, Samanta Etel Treiger, et al.
Publicado: (2013)

Pediculosis capitis among Primary School Children and Related Risk Factors in Urmia, the Main City of West Azarbaijan, Iran
por: Tappeh, K Hazrati, et al.
Publicado: (2012)

The Route of Leishmania tropica Infection Determines Disease Outcome and Protection against Leishmania major in BALB/c Mice
por: Mahmoudzadeh-Niknam, Hamid, et al.
Publicado: (2013)

Attenuated Leishmania major Induce a High Level of Protection against Leishmania infantum in BALB/c Mice
por: NOORPISHEH GHADIMI, Shamsi, et al.
Publicado: (2019)

In Vitro Antileishmanial Effects of Saffron Compounds, Crocin and Stigmasterol, on Iranian Strain of Leishmania major (MHOM/IR/75/ER)
por: RANJBAR, Reza, et al.
Publicado: (2021)

Genetic Characterization of Fasciola Isolates from West Azerbaijan Province Iran Based on ITS1 and ITS2 Sequence of Ribosomal DNA
por: GALAVANI, Hossein, et al.
Publicado: (2016)

Immunization Against Cutaneous Leishmaniasis by Alginate Microspheres Loaded With Autoclaved Leishmania Major (ALM) and Quillaja Saponins
por: Tafaghodi, Mohsen, et al.
Publicado: (2016)

The Multiple Forms of Leishmania major in BALB/C Mice Lung in Iran
por: Shirbazou, SH, et al.
Publicado: (2012)

Visualization of Leishmania tropica Infection in BALB/c Mice by Bioluminescence Imaging
por: Eskandar, Mahdieh, et al.
Publicado: (2020)

Evaluation of Toll-Like Receptor 11 Agonist Adjuvant Activity in Immunization of BALB/c Mice with Total Lysate Antigens of Toxoplasma gondii RH Strain
por: SHOKRI, Meysam, et al.
Publicado: (2020)

The Anti-leishmanial Efficacy of Artemisia dracunculus Ethanolic Extract in Vitro and Its Effects on IFN-γ and IL-4 Response
por: REZAEI, Reza, et al.
Publicado: (2017)

Draft Genome Sequences of Leishmania (Leishmania) amazonensis, Leishmania (Leishmania) mexicana, and Leishmania (Leishmania) aethiopica, Potential Etiological Agents of Diffuse Cutaneous Leishmaniasis
por: Batra, Dhwani, et al.
Publicado: (2019)

IL-4-deficient Balb/c mice resist infection with Leishmania major
Publicado: (1996)

Berberine-Loaded Liposomes for the Treatment of Leishmania infantum-Infected BALB/c Mice
por: Calvo, Alba, et al.
Publicado: (2020)

Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes
por: Fortéa, José Osorio y, et al.
Publicado: (2009)

Phenotypic diversity and selection maintain Leishmania amazonensis infectivity in BALB/c mouse model
por: Espiau, Benoît, et al.
Publicado: (2017)

Photodynamic Vaccination of BALB/c Mice for Prophylaxis of Cutaneous Leishmaniasis Caused by Leishmania amazonensis
por: Viana, Sayonara M., et al.
Publicado: (2018)

Pharmacokinetics of neutron-irradiated meglumine antimoniate in Leishmania amazonensis-infected BALB/c mice
por: Borborema, Samanta Etel Treiger, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7tsdn4guid799a5h7efj97cp03