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Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia

BACKGROUND: Activated microglial cells release an excess of inflammatory mediators after an ischemic stroke. We reported previously that scutellarin effectively suppressed the inflammatory response induced by activated microglia in rats subjected to middle cerebral artery occlusion (MCAO); however,...

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Detalles Bibliográficos
Autores principales:	Yuan, Yun, Rangarajan, Parakalan, Kan, Enci Mary, Wu, Yajun, Wu, Chunyun, Ling, Eng-Ang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316603/ https://www.ncbi.nlm.nih.gov/pubmed/25600517 http://dx.doi.org/10.1186/s12974-014-0226-z

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