Endothelial destabilization by angiopoietin-2 via integrin β1 activation

Angiopoietins regulate vascular homeostasis via the endothelial Tie receptor tyrosine kinases. Angiopoietin-1 (Ang1) supports endothelial stabilization via Tie2 activation. Angiopoietin-2 (Ang2) functions as a context-dependent Tie2 agonist/antagonist promoting pathological angiogenesis, vascular pe...

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Detalles Bibliográficos
Autores principales: Hakanpaa, Laura, Sipila, Tuomas, Leppanen, Veli-Matti, Gautam, Prson, Nurmi, Harri, Jacquemet, Guillaume, Eklund, Lauri, Ivaska, Johanna, Alitalo, Kari, Saharinen, Pipsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316742/
https://www.ncbi.nlm.nih.gov/pubmed/25635707
http://dx.doi.org/10.1038/ncomms6962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316742/
https://www.ncbi.nlm.nih.gov/pubmed/25635707
http://dx.doi.org/10.1038/ncomms6962

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