Interleukin-17A promotes functional activation of systemic sclerosis patient-derived dermal vascular smooth muscle cells by extracellular-regulated protein kinases signalling pathway

INTRODUCTION: Dermal vascular smooth muscle cells (DVSMCs) are important for vascular wall fibrosis in microangiopathy of systemic sclerosis (SSc). T helper 17 cell-associated cytokines, particularly interleukin-17A (IL-17A), have been demonstrated to play a role in the pathogenesis of SSc. However,...

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Detalles Bibliográficos
Autores principales: Liu, Mengguo, Yang, Ji, Xing, Xiaojing, Cui, Xiangxiang, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316765/
https://www.ncbi.nlm.nih.gov/pubmed/25551434
http://dx.doi.org/10.1186/s13075-014-0512-2

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