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DNA damage response and evasion from immunosurveillance in CLL: new options for NK cell-based immunotherapies
Chronic lymphocytic leukemia (CLL) is the most prominent B cell malignancy among adults in the Western world and characterized by a clonal expansion of B cells. The patients suffer from severe immune defects resulting in increased susceptibility to infections and failure to generate an antitumor imm...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316781/ https://www.ncbi.nlm.nih.gov/pubmed/25699074 http://dx.doi.org/10.3389/fgene.2015.00011 |