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Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating macrophages with alteration of the TIMP-1/MMP2/MMP9 signals

BACKGROUND: TR4 nuclear receptor 4 (TR4) plays an important role in macrophages-associated foam cell formation of cardiovascular diseases and infiltrating macrophages are critical for prostate cancer (PCa) progression. However, the linkage of macrophages and TR4 and their impacts on PCa metastasis r...

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Detalles Bibliográficos
Autores principales:	Ding, Xianfan, Yang, Dong-Rong, Xia, Liqun, Chen, Bide, Yu, Shicheng, Niu, Yuanjie, Wang, Mingchao, Li, Gonghui, Chang, Chawnshang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316804/ https://www.ncbi.nlm.nih.gov/pubmed/25623427 http://dx.doi.org/10.1186/s12943-014-0281-1

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