A+-Helix of Protein C Inhibitor (PCI) Is a Cell-penetrating Peptide That Mediates Cell Membrane Permeation of PCI

Protein C inhibitor (PCI) is a serpin with broad protease reactivity. It binds glycosaminoglycans and certain phospholipids that can modulate its inhibitory activity. PCI can penetrate through cellular membranes via binding to phosphatidylethanolamine. The exact mechanism of PCI internalization and...

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Detalles Bibliográficos
Autores principales: Yang, Hanjiang, Wahlmüller, Felix Christof, Sarg, Bettina, Furtmüller, Margareta, Geiger, Margarethe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317013/
https://www.ncbi.nlm.nih.gov/pubmed/25488662
http://dx.doi.org/10.1074/jbc.M114.581736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317013/
https://www.ncbi.nlm.nih.gov/pubmed/25488662
http://dx.doi.org/10.1074/jbc.M114.581736

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