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Acceleration of α-Synuclein Aggregation by Exosomes

Exosomes are small vesicles released from cells into extracellular space. We have isolated exosomes from neuroblastoma cells and investigated their influence on the aggregation of α-synuclein, a protein associated with Parkinson disease pathology. Using cryo-transmission electron microscopy of exoso...

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Detalles Bibliográficos
Autores principales: Grey, Marie, Dunning, Christopher J., Gaspar, Ricardo, Grey, Carl, Brundin, Patrik, Sparr, Emma, Linse, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317028/
https://www.ncbi.nlm.nih.gov/pubmed/25425650
http://dx.doi.org/10.1074/jbc.M114.585703

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