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Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling

[Image: see text] Rectifying nanopores feature ion currents that are higher for voltages of one polarity compared to the currents recorded for corresponding voltages of the opposite polarity. Rectification of nanopores has been found to depend on the pore opening diameter and distribution of surface...

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Autores principales: Gamble, Trevor, Decker, Karl, Plett, Timothy S., Pevarnik, Matthew, Pietschmann, Jan-Frederik, Vlassiouk, Ivan, Aksimentiev, Aleksei, Siwy, Zuzanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317049/
https://www.ncbi.nlm.nih.gov/pubmed/25678940
http://dx.doi.org/10.1021/jp501492g
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author Gamble, Trevor
Decker, Karl
Plett, Timothy S.
Pevarnik, Matthew
Pietschmann, Jan-Frederik
Vlassiouk, Ivan
Aksimentiev, Aleksei
Siwy, Zuzanna S.
author_facet Gamble, Trevor
Decker, Karl
Plett, Timothy S.
Pevarnik, Matthew
Pietschmann, Jan-Frederik
Vlassiouk, Ivan
Aksimentiev, Aleksei
Siwy, Zuzanna S.
author_sort Gamble, Trevor
collection PubMed
description [Image: see text] Rectifying nanopores feature ion currents that are higher for voltages of one polarity compared to the currents recorded for corresponding voltages of the opposite polarity. Rectification of nanopores has been found to depend on the pore opening diameter and distribution of surface charges on the pore walls as well as pore geometry. Very little is known, however, on the dependence of ionic rectification on the type of transported ions of the same charge. We performed experiments with single conically shaped nanopores in a polymer film and recorded current–voltage curves in three electrolytes: LiCl, NaCl, and KCl. Rectification degrees of the pores, quantified as the ratio of currents recorded for voltages of opposite polarities, were the highest for KCl and the lowest for LiCl. The experimental observations could not be explained by a continuum modeling based on the Poisson–Nernst–Planck equations. All-atom molecular dynamics simulations revealed differential binding between Li(+), Na(+), and K(+) ions and carboxyl groups on the pore walls, resulting in changes to both the effective surface charge of the nanopore and cation mobility within the pore.
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spelling pubmed-43170492015-04-14 Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling Gamble, Trevor Decker, Karl Plett, Timothy S. Pevarnik, Matthew Pietschmann, Jan-Frederik Vlassiouk, Ivan Aksimentiev, Aleksei Siwy, Zuzanna S. J Phys Chem C Nanomater Interfaces [Image: see text] Rectifying nanopores feature ion currents that are higher for voltages of one polarity compared to the currents recorded for corresponding voltages of the opposite polarity. Rectification of nanopores has been found to depend on the pore opening diameter and distribution of surface charges on the pore walls as well as pore geometry. Very little is known, however, on the dependence of ionic rectification on the type of transported ions of the same charge. We performed experiments with single conically shaped nanopores in a polymer film and recorded current–voltage curves in three electrolytes: LiCl, NaCl, and KCl. Rectification degrees of the pores, quantified as the ratio of currents recorded for voltages of opposite polarities, were the highest for KCl and the lowest for LiCl. The experimental observations could not be explained by a continuum modeling based on the Poisson–Nernst–Planck equations. All-atom molecular dynamics simulations revealed differential binding between Li(+), Na(+), and K(+) ions and carboxyl groups on the pore walls, resulting in changes to both the effective surface charge of the nanopore and cation mobility within the pore. American Chemical Society 2014-04-14 2014-05-08 /pmc/articles/PMC4317049/ /pubmed/25678940 http://dx.doi.org/10.1021/jp501492g Text en Copyright © 2014 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Gamble, Trevor
Decker, Karl
Plett, Timothy S.
Pevarnik, Matthew
Pietschmann, Jan-Frederik
Vlassiouk, Ivan
Aksimentiev, Aleksei
Siwy, Zuzanna S.
Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling
title Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling
title_full Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling
title_fullStr Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling
title_full_unstemmed Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling
title_short Rectification of Ion Current in Nanopores Depends on the Type of Monovalent Cations: Experiments and Modeling
title_sort rectification of ion current in nanopores depends on the type of monovalent cations: experiments and modeling
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317049/
https://www.ncbi.nlm.nih.gov/pubmed/25678940
http://dx.doi.org/10.1021/jp501492g
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