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Celiac disease causing severe osteomalacia: an association still present in Morocco!
Celiac disease (CD), a malabsorption syndrome caused by hypersensitivity to gliadin fraction of gluten. CD can manifest with classic symptoms; however, significant myopathy and multiple fractures are rarely the predominant presentation of untreated celiac disease. Osteomalacia complicating celiac di...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317067/ https://www.ncbi.nlm.nih.gov/pubmed/25667705 http://dx.doi.org/10.11604/pamj.2014.19.43.2757 |
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author | Tahiri, Latifa Azzouzi, Hamida Squalli, Ghita Abourazzak, Fatimazahra Harzy, Taoufik |
author_facet | Tahiri, Latifa Azzouzi, Hamida Squalli, Ghita Abourazzak, Fatimazahra Harzy, Taoufik |
author_sort | Tahiri, Latifa |
collection | PubMed |
description | Celiac disease (CD), a malabsorption syndrome caused by hypersensitivity to gliadin fraction of gluten. CD can manifest with classic symptoms; however, significant myopathy and multiple fractures are rarely the predominant presentation of untreated celiac disease. Osteomalacia complicating celiac disease had become more and more rare. We describe here a case of osteomalacia secondary to a longstanding untreated celiac disease. This patient complained about progressive bone and muscular pain, weakness, fractures and skeletal deformities. Radiological and laboratory findings were all in favor of severe osteomalacia. Improvement of patient's weakness and laboratory abnormalities was obvious after treatment with gluten free diet, vitamin D, calcium and iron. This case affirms that chronic untreated celiac disease, can lead to an important bone loss and irreversible complications like skeletal deformities. |
format | Online Article Text |
id | pubmed-4317067 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-43170672015-02-09 Celiac disease causing severe osteomalacia: an association still present in Morocco! Tahiri, Latifa Azzouzi, Hamida Squalli, Ghita Abourazzak, Fatimazahra Harzy, Taoufik Pan Afr Med J Case Report Celiac disease (CD), a malabsorption syndrome caused by hypersensitivity to gliadin fraction of gluten. CD can manifest with classic symptoms; however, significant myopathy and multiple fractures are rarely the predominant presentation of untreated celiac disease. Osteomalacia complicating celiac disease had become more and more rare. We describe here a case of osteomalacia secondary to a longstanding untreated celiac disease. This patient complained about progressive bone and muscular pain, weakness, fractures and skeletal deformities. Radiological and laboratory findings were all in favor of severe osteomalacia. Improvement of patient's weakness and laboratory abnormalities was obvious after treatment with gluten free diet, vitamin D, calcium and iron. This case affirms that chronic untreated celiac disease, can lead to an important bone loss and irreversible complications like skeletal deformities. The African Field Epidemiology Network 2014-09-19 /pmc/articles/PMC4317067/ /pubmed/25667705 http://dx.doi.org/10.11604/pamj.2014.19.43.2757 Text en © Latifa Tahiri et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Tahiri, Latifa Azzouzi, Hamida Squalli, Ghita Abourazzak, Fatimazahra Harzy, Taoufik Celiac disease causing severe osteomalacia: an association still present in Morocco! |
title | Celiac disease causing severe osteomalacia: an association still present in Morocco! |
title_full | Celiac disease causing severe osteomalacia: an association still present in Morocco! |
title_fullStr | Celiac disease causing severe osteomalacia: an association still present in Morocco! |
title_full_unstemmed | Celiac disease causing severe osteomalacia: an association still present in Morocco! |
title_short | Celiac disease causing severe osteomalacia: an association still present in Morocco! |
title_sort | celiac disease causing severe osteomalacia: an association still present in morocco! |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317067/ https://www.ncbi.nlm.nih.gov/pubmed/25667705 http://dx.doi.org/10.11604/pamj.2014.19.43.2757 |
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