Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

The gene regulatory network (GRN) that supports neural stem cell (NS cell) self-renewal has so far been poorly characterized. Knowledge of the central transcription factors (TFs), the noncoding gene regulatory regions that they bind to, and the genes whose expression they modulate will be crucial in...

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Detalles Bibliográficos
Autores principales: Mateo, Juan L., van den Berg, Debbie L.C., Haeussler, Maximilian, Drechsel, Daniela, Gaber, Zachary B., Castro, Diogo S., Robson, Paul, Crawford, Gregory E., Flicek, Paul, Ettwiller, Laurence, Wittbrodt, Joachim, Guillemot, François, Martynoga, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317172/
https://www.ncbi.nlm.nih.gov/pubmed/25294244
http://dx.doi.org/10.1101/gr.173435.114

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