Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient

This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correlation of CACNA1C with Brugada and Bipolar suggests allelic disequilibriu...

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Autores principales: Crawford, Rebecca R, Higdon, Ashlee N, Casey, David B, Good, David E, Mungrue, Imran N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317204/
https://www.ncbi.nlm.nih.gov/pubmed/25678966
http://dx.doi.org/10.1002/ccr3.136
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author Crawford, Rebecca R
Higdon, Ashlee N
Casey, David B
Good, David E
Mungrue, Imran N
author_facet Crawford, Rebecca R
Higdon, Ashlee N
Casey, David B
Good, David E
Mungrue, Imran N
author_sort Crawford, Rebecca R
collection PubMed
description This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correlation of CACNA1C with Brugada and Bipolar suggests allelic disequilibrium, leading to a subpopulation of bipolar patients sensitive to arrhythmia.
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spelling pubmed-43172042015-02-12 Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient Crawford, Rebecca R Higdon, Ashlee N Casey, David B Good, David E Mungrue, Imran N Clin Case Rep Case Reports This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correlation of CACNA1C with Brugada and Bipolar suggests allelic disequilibrium, leading to a subpopulation of bipolar patients sensitive to arrhythmia. BlackWell Publishing Ltd 2015-01 2014-10-22 /pmc/articles/PMC4317204/ /pubmed/25678966 http://dx.doi.org/10.1002/ccr3.136 Text en © 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Crawford, Rebecca R
Higdon, Ashlee N
Casey, David B
Good, David E
Mungrue, Imran N
Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
title Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
title_full Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
title_fullStr Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
title_full_unstemmed Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
title_short Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient
title_sort multiple lithium-dependent brugada syndrome unmasking events in a bipolar patient
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317204/
https://www.ncbi.nlm.nih.gov/pubmed/25678966
http://dx.doi.org/10.1002/ccr3.136
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