A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis

Gamma–delta T-cell lymphomas (GD-TCL) are rare and rapidly fatal neoplasms that are often associated with Hemophagocytic Lymphohistiocytosis (HLH), a syndrome of fevers, cytopenias, and multiorgan failure that often leads to a rapid death. We report the first case demonstrating an association betwee...

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Autores principales: Gibson, Juliet Fraser, Kapur, Lucy, Sokhn, Joseph, Xu, Mina, Foss, Francine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317209/
https://www.ncbi.nlm.nih.gov/pubmed/25678971
http://dx.doi.org/10.1002/ccr3.142
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author Gibson, Juliet Fraser
Kapur, Lucy
Sokhn, Joseph
Xu, Mina
Foss, Francine M
author_facet Gibson, Juliet Fraser
Kapur, Lucy
Sokhn, Joseph
Xu, Mina
Foss, Francine M
author_sort Gibson, Juliet Fraser
collection PubMed
description Gamma–delta T-cell lymphomas (GD-TCL) are rare and rapidly fatal neoplasms that are often associated with Hemophagocytic Lymphohistiocytosis (HLH), a syndrome of fevers, cytopenias, and multiorgan failure that often leads to a rapid death. We report the first case demonstrating an association between GD-TCL, HLH, and cardiac amyloidosis, presenting a novel mechanism for rapid deterioration in these patients.
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spelling pubmed-43172092015-02-12 A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis Gibson, Juliet Fraser Kapur, Lucy Sokhn, Joseph Xu, Mina Foss, Francine M Clin Case Rep Case Reports Gamma–delta T-cell lymphomas (GD-TCL) are rare and rapidly fatal neoplasms that are often associated with Hemophagocytic Lymphohistiocytosis (HLH), a syndrome of fevers, cytopenias, and multiorgan failure that often leads to a rapid death. We report the first case demonstrating an association between GD-TCL, HLH, and cardiac amyloidosis, presenting a novel mechanism for rapid deterioration in these patients. BlackWell Publishing Ltd 2015-01 2014-11-17 /pmc/articles/PMC4317209/ /pubmed/25678971 http://dx.doi.org/10.1002/ccr3.142 Text en © 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Gibson, Juliet Fraser
Kapur, Lucy
Sokhn, Joseph
Xu, Mina
Foss, Francine M
A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis
title A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis
title_full A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis
title_fullStr A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis
title_full_unstemmed A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis
title_short A fatal case of primary cutaneous gamma–delta T-cell lymphoma complicated by HLH and cardiac amyloidosis
title_sort fatal case of primary cutaneous gamma–delta t-cell lymphoma complicated by hlh and cardiac amyloidosis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317209/
https://www.ncbi.nlm.nih.gov/pubmed/25678971
http://dx.doi.org/10.1002/ccr3.142
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