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Varenicline enhances dopamine release facilitation more than nicotine after long-term nicotine treatment and withdrawal

An important factor contributing to the high relapse rates among smokers is nicotine withdrawal symptoms. Multiple studies suggest that decreased dopamine release in nucleus accumbens plays a key role in withdrawal. However, recent reports showed that long-term nicotine exposure itself also decrease...

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Detalles Bibliográficos
Autores principales:	Perez, Xiomara A, Khroyan, Taline V, McIntosh, J Michael, Quik, Maryka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317236/ https://www.ncbi.nlm.nih.gov/pubmed/25692023 http://dx.doi.org/10.1002/prp2.105

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