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Identification of trichlormethiazide as a Mdr1a/b gene expression enhancer via a dual secretion-based promoter assay

Transporters of the ATP-binding cassette (ABC) family such as MDR1 play a pivotal role in persistence of brain homeostasis by contributing to the strict permeability properties of the blood–brain barrier. This barrier on one hand compromises treatment of central nervous system diseases by restrictin...

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Detalles Bibliográficos
Autores principales:	Schulze, Sarina, Reinhardt, Sven, Freese, Christian, Schmitt, Ulrich, Endres, Kristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317239/ https://www.ncbi.nlm.nih.gov/pubmed/25692026 http://dx.doi.org/10.1002/prp2.109

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