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Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5
Augmented AMP-activated protein kinase (AMPK) activity inhibits cell migration, possibly contributing to the clinical benefits of chemical AMPK activators in preventing atherosclerosis, vascular remodelling and cancer metastasis. However, the underlying mechanisms remain largely unknown. Here we ide...
Autores principales: | Yan, Yi, Tsukamoto, Osamu, Nakano, Atsushi, Kato, Hisakazu, Kioka, Hidetaka, Ito, Noriaki, Higo, Shuichiro, Yamazaki, Satoru, Shintani, Yasunori, Matsuoka, Ken, Liao, Yulin, Asanuma, Hiroshi, Asakura, Masanori, Takafuji, Kazuaki, Minamino, Tetsuo, Asano, Yoshihiro, Kitakaze, Masafumi, Takashima, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317497/ https://www.ncbi.nlm.nih.gov/pubmed/25635515 http://dx.doi.org/10.1038/ncomms7137 |
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