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In Vitro Gender-Dependent Inhibition of Porcine Cytochrome P450 Activity by Selected Flavonoids and Phenolic Acids

We investigated gender-related differences in the ability of selected flavonoids and phenolic compounds to modify porcine hepatic CYP450-dependent activity. Using pools of microsomes from male and female pigs, the inhibition of the CYP families 1A, 2A, 2E1, and 3A was determined. The specific CYP ac...

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Detalles Bibliográficos
Autores principales: Ekstrand, Bo, Rasmussen, Martin Krøyer, Woll, Felicia, Zlabek, Vladimir, Zamaratskaia, Galia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317639/
https://www.ncbi.nlm.nih.gov/pubmed/25685784
http://dx.doi.org/10.1155/2015/387918