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Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation

Axonal outgrowth inhibitors and scar formation are two major obstacles to central nervous system (CNS) repair. No target molecule that regulates both axonal growth and scarring has been identified. Here we identified collapsin response mediator protein 4 (CRMP4), a common mediator of inhibitory sign...

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Detalles Bibliográficos
Autores principales: Nagai, Jun, Kitamura, Yoshiteru, Owada, Kazuki, Yamashita, Naoya, Takei, Kohtaro, Goshima, Yoshio, Ohshima, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317684/
https://www.ncbi.nlm.nih.gov/pubmed/25652774
http://dx.doi.org/10.1038/srep08269