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Cullin Family Proteins and Tumorigenesis: Genetic Association and Molecular Mechanisms

Cullin family proteins function as scaffolds to form numerous E3 ubiquitin ligases with RING proteins, adaptor proteins and substrate recognition receptors. These E3 ligases further recognize numerous substrates to participate in a variety of cellular processes, such as DNA damage and repair, cell d...

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Detalles Bibliográficos
Autores principales: Chen, Zhi, Sui, Jie, Zhang, Fan, Zhang, Caiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317758/
https://www.ncbi.nlm.nih.gov/pubmed/25663940
http://dx.doi.org/10.7150/jca.11076