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Microparticles induce multifactorial resistance through oncogenic pathways independently of cancer cell type

Multidrug resistance (MDR) is considered a multifactorial event that favors cancer cells becoming resistant to several chemotherapeutic agents. Numerous mechanisms contribute to MDR, such as P-glycoprotein (Pgp/ABCB1) activity that promotes drug efflux, overexpression of inhibitors of apoptosis prot...

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Detalles Bibliográficos
Autores principales: de Souza, Paloma Silva, Cruz, André LS, Viola, João PB, Maia, Raquel C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317771/
https://www.ncbi.nlm.nih.gov/pubmed/25457412
http://dx.doi.org/10.1111/cas.12566

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