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High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids

Non-muscle invasive bladder cancer is treated with intravesical chemotherapy (IVC) after transurethral resection (TUR) to reduce the probability of recurrence. Despite improvement, the recurrence rate remains high. Intravesical chemotherapeutics at high doses are expected to ablate unresected tumors...

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Detalles Bibliográficos
Autores principales: Yoshida, Takahiro, Okuyama, Hiroaki, Nakayama, Masashi, Endo, Hiroko, Nonomura, Norio, Nishimura, Kazuo, Inoue, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317779/
https://www.ncbi.nlm.nih.gov/pubmed/25363302
http://dx.doi.org/10.1111/cas.12567