Cargando…

Interleukin-6 induces malignant transformation of rat mesenchymal stem cells in association with enhanced signaling of signal transducer and activator of transcription 3

Mesenchymal stem cells (MSCs) have the potential to be the source for cell-based therapies. However, MSCs can undergo malignant transformation in a tumor microenvironment where a high level of interleukin (IL)-6 is present. In this study, we investigated the role of IL-6 and signal transducer and ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Xiangrong, Liu, Jianping, Bai, Lu, Tian, Jie, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317870/
https://www.ncbi.nlm.nih.gov/pubmed/24168060
http://dx.doi.org/10.1111/cas.12313