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Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is a membrane-bound serine protease inhibitor that is expressed on the surface of epithelial and carcinoma cells. On the cell surface, HAI-1 regulates membrane-anchored serine proteases, with matriptase being the most critical target. Matri...
Autores principales: | Ye, Jingjia, Kawaguchi, Makiko, Haruyama, Yukihiro, Kanemaru, Ai, Fukushima, Tsuyoshi, Yamamoto, Koji, Lin, Chen-Yong, Kataoka, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317873/ https://www.ncbi.nlm.nih.gov/pubmed/24147538 http://dx.doi.org/10.1111/cas.12306 |
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