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High antitumor activity of pladienolide B and its derivative in gastric cancer
The antitumor activity of pladienolide B, a novel splicing inhibitor, against gastric cancer is totally unknown and no predictive biomarker of pladienolide B efficacy has been reported. We investigated the antitumor activity of pladienolide B and its derivative on gastric cancer cell lines and prima...
Autores principales: | Sato, Momoko, Muguruma, Naoki, Nakagawa, Tadahiko, Okamoto, Koichi, Kimura, Tetsuo, Kitamura, Shinji, Yano, Hiromi, Sannomiya, Katsutaka, Goji, Takahiro, Miyamoto, Hiroshi, Okahisa, Toshiya, Mikasa, Hiroaki, Wada, Satoshi, Iwata, Masao, Takayama, Tetsuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317874/ https://www.ncbi.nlm.nih.gov/pubmed/24635824 http://dx.doi.org/10.1111/cas.12317 |
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