Loss of B-cell translocation gene 2 expression in estrogen receptor-positive breast cancer predicts tamoxifen resistance

B-cell translocation gene 2 (BTG2), a gene suppressed in a subset of aggressive breast cancer, is repressed by estrogen. BTG2 inhibits the expression of HER ligands and promotes AKT activation, which plays an essential role in the tamoxifen resistance of estrogen receptor (ER)-positive breast cancer...

Descripción completa

Detalles Bibliográficos
Autores principales: Takahashi, Maiko, Hayashida, Tetsu, Okazaki, Hiroshi, Miyao, Kazuhiro, Jinno, Hiromitsu, Kitagawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317889/
https://www.ncbi.nlm.nih.gov/pubmed/24698107
http://dx.doi.org/10.1111/cas.12410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317889/
https://www.ncbi.nlm.nih.gov/pubmed/24698107
http://dx.doi.org/10.1111/cas.12410

Ejemplares similares