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Peroxisome proliferator-activated receptor γ agonist efatutazone impairs transforming growth factor β2-induced motility of epidermal growth factor receptor tyrosine kinase inhibitor-resistant lung cancer cells

Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) are effective for non-small cell lung cancers (NSCLC) with EGFR-activating mutations. However, most responders develop resistance. Efatutazone, a novel peroxisome proliferator-activated receptor gamma (PPARγ) agonist, is currentl...

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Detalles Bibliográficos
Autores principales:	Serizawa, Masakuni, Murakami, Haruyasu, Watanabe, Masaru, Takahashi, Toshiaki, Yamamoto, Nobuyuki, Koh, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317891/ https://www.ncbi.nlm.nih.gov/pubmed/24698130 http://dx.doi.org/10.1111/cas.12411

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