Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone

Giant cell tumors of bone (GCTB) are benign and locally destructive tumors that include osteoclast-type multinuclear giant cells. No available treatment is definitively effective in curing GCTB, especially in surgically unresectable cases. Isocitrate dehydrogenase (IDH) mutations have been reported...

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Detalles Bibliográficos
Autores principales: Kato Kaneko, Mika, Liu, Xing, Oki, Hiroharu, Ogasawara, Satoshi, Nakamura, Takuro, Saidoh, Noriko, Tsujimoto, Yuta, Matsuyama, Yuka, Uruno, Akira, Sugawara, Masato, Tsuchiya, Takashi, Yamakawa, Mitsunori, Yamamoto, Masayuki, Takagi, Michiaki, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317903/
https://www.ncbi.nlm.nih.gov/pubmed/24898068
http://dx.doi.org/10.1111/cas.12413

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