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Phase I study of olaratumab in Japanese patients with advanced solid tumors
Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody that selectively binds the external domain of human platelet-derived growth factor receptor-α with high affinity and blocks ligand binding. This was a single-center, dose-escalation, phase I trial of olaratumab in Japanese patients with...
Autores principales: | Doi, Toshihiko, Ma, Yan, Dontabhaktuni, Aruna, Nippgen, Cornelia, Nippgen, Johannes, Ohtsu, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317910/ https://www.ncbi.nlm.nih.gov/pubmed/24816152 http://dx.doi.org/10.1111/cas.12444 |
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