Cargando…
TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells
TMEPAI/PMEPA1 is a transmembrane protein that was originally identified as a prostatic RNA, the synthesis of which is induced by testosterone or its derivatives. We have recently identified TMEPAI as a direct target gene of transforming growth factor-β (TGF-β)/Smad signaling that participates in neg...
Autores principales: | Vo Nguyen, Thanh Thao, Watanabe, Yukihide, Shiba, Aya, Noguchi, Masayuki, Itoh, Susumu, Kato, Mitsuyasu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317935/ https://www.ncbi.nlm.nih.gov/pubmed/24438557 http://dx.doi.org/10.1111/cas.12355 |
Ejemplares similares
-
PMEPA1/TMEPAI Is a Unique Tumorigenic Activator of AKT Promoting Proteasomal Degradation of PHLPP1 in Triple-Negative Breast Cancer Cells
por: Haque, Md. Anwarul, et al.
Publicado: (2021) -
TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass
por: Hagg, Adam, et al.
Publicado: (2020) -
TGF-β-Induced TMEPAI Attenuates the Response of Triple-Negative Breast Cancer Cells to Doxorubicin and Paclitaxel
por: Wardhani, Bantari WK, et al.
Publicado: (2020) -
TGF-β-Induced TMEPAI Promotes Epithelial–Mesenchymal Transition in Doxorubicin-Treated Triple-Negative Breast Cancer Cells via SMAD3 and PI3K/AKT Pathway Alteration
por: Wardhani, Bantari W K, et al.
Publicado: (2021) -
Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer
por: Singha, Prajjal K., et al.
Publicado: (2019)