IDH2 and TP53 mutations are correlated with gliomagenesis in a patient with Maffucci syndrome

We report on a 24-year-old woman who was diagnosed as having Maffucci syndrome with anaplastic astrocytoma. We analyzed the IDH1 and IDH2 mutations of enchondroma, hemangioma and anaplastic astrocytoma tissues and the same somatic mosaic mutation in IDH2 gene was identified in all these tissues. In...

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Detalles Bibliográficos
Autores principales: Moriya, Kunihiko, Kaneko, Mika K, Liu, Xing, Hosaka, Masami, Fujishima, Fumiyoshi, Sakuma, Jun, Ogasawara, Satoshi, Watanabe, Mika, Sasahara, Yoji, Kure, Shigeo, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317937/
https://www.ncbi.nlm.nih.gov/pubmed/24344754
http://dx.doi.org/10.1111/cas.12337

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