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5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation
Cell migration is an essential step for tumor metastasis. The small GTPase Rac1 plays an important role in cell migration. Previously, we reported that epidermal growth factor (EGF) induced two waves of Rac1 activation; namely, at 5 min and 12 h after stimulation. A second wave of EGF-induced Rac1 a...
Autores principales: | Magi, Shigeyuki, Takemoto, Yasushi, Kobayashi, Hiroki, Kasamatsu, Masato, Akita, Takahiro, Tanaka, Ayako, Takano, Kei, Tashiro, Etsu, Igarashi, Yasuhiro, Imoto, Masaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317946/ https://www.ncbi.nlm.nih.gov/pubmed/24350867 http://dx.doi.org/10.1111/cas.12340 |
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