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Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability
Double-strand breaks (DSBs) are one of the severest types of DNA damage. Unrepaired DSBs easily induce cell death and chromosome aberrations. To maintain genomic stability, cells have checkpoint and DSB repair systems to respond to DNA damage throughout most of the cell cycle. The failure of this pr...
Autores principales: | Terasawa, Masahiro, Shinohara, Akira, Shinohara, Miki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317954/ https://www.ncbi.nlm.nih.gov/pubmed/25287622 http://dx.doi.org/10.1111/cas.12551 |
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