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Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment

RNAi enables potent and specific gene silencing, potentially offering useful means for treatment of cancers. However, safe and efficient drug delivery systems (DDS) that are appropriate for intra-tumor delivery of siRNA or shRNA have rarely been established, hindering clinical application of RNAi te...

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Detalles Bibliográficos
Autores principales:	Fujii, Hidetaka, Shin-Ya, Masaharu, Takeda, Shigeo, Hashimoto, Yoshihide, Mukai, Sada-atsu, Sawada, Shin-ichi, Adachi, Tetsuya, Akiyoshi, Kazunari, Miki, Tsuneharu, Mazda, Osam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317968/ https://www.ncbi.nlm.nih.gov/pubmed/25283373 http://dx.doi.org/10.1111/cas.12547

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