Cargando…
Oral Lichenoid Lesions - A Review and Update
BACKGROUND: Oral lichenoid lesions or reactions (OLLs/OLRs) are clinical and histological contemporaries of the classical oral lichen planus (OLP) that have generated a lot of debate in literature. In contrast to the idiopathic nature of OLP, OLLs are often associated with a known identifiable incit...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318020/ https://www.ncbi.nlm.nih.gov/pubmed/25657414 http://dx.doi.org/10.4103/0019-5154.147830 |
_version_ | 1782355781739347968 |
---|---|
author | Kamath, Venkatesh Vishwanath Setlur, Krishnanand Yerlagudda, Komali |
author_facet | Kamath, Venkatesh Vishwanath Setlur, Krishnanand Yerlagudda, Komali |
author_sort | Kamath, Venkatesh Vishwanath |
collection | PubMed |
description | BACKGROUND: Oral lichenoid lesions or reactions (OLLs/OLRs) are clinical and histological contemporaries of the classical oral lichen planus (OLP) that have generated a lot of debate in literature. In contrast to the idiopathic nature of OLP, OLLs are often associated with a known identifiable inciting factor. A superficial examination of these lesions clinically and histologically often reveals many similarities with OLP, but recent data indicate that distinguishable features do exist and form the basis of most classifications. AIMS AND OBJECTIVES: This paper attempts to collate available data in English literature on OLLs, highlight distinguishing features clinically and histologically and reflect on the malignant transformation potential and treatment modalities of the condition. MATERIALS AND METHODS: A comprehensive search of medical and dental databases including PubMed, Ovid, Cochrane, Pubget, Researchgate, and non-medical search engines were utilized for the review. The search words included “oral lichen planus”, “oral lichenoid lesions”, “oral drug reactions”, “lichenoid dysplasia”, and “adverse effects of dental materials”. REVIEW RESULTS: OLLs seem to grossly underrated and most cases were clubbed as OLP. Definite clinical and histological features were uncovered to establish the identity of this lesion. Associations with dental restorative materials, drugs, and medications have been conclusively proven in the etiology of this condition. Specific markers are being utilized to diagnose the condition and monitor its progress. CONCLUSION: Substantial differentiating features were uncovered to delineate OLLs as a separate entity with definite etiology, pathogenesis, and a high malignant transformation rate compared with OLP. |
format | Online Article Text |
id | pubmed-4318020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43180202015-02-05 Oral Lichenoid Lesions - A Review and Update Kamath, Venkatesh Vishwanath Setlur, Krishnanand Yerlagudda, Komali Indian J Dermatol E-IJD Review Article BACKGROUND: Oral lichenoid lesions or reactions (OLLs/OLRs) are clinical and histological contemporaries of the classical oral lichen planus (OLP) that have generated a lot of debate in literature. In contrast to the idiopathic nature of OLP, OLLs are often associated with a known identifiable inciting factor. A superficial examination of these lesions clinically and histologically often reveals many similarities with OLP, but recent data indicate that distinguishable features do exist and form the basis of most classifications. AIMS AND OBJECTIVES: This paper attempts to collate available data in English literature on OLLs, highlight distinguishing features clinically and histologically and reflect on the malignant transformation potential and treatment modalities of the condition. MATERIALS AND METHODS: A comprehensive search of medical and dental databases including PubMed, Ovid, Cochrane, Pubget, Researchgate, and non-medical search engines were utilized for the review. The search words included “oral lichen planus”, “oral lichenoid lesions”, “oral drug reactions”, “lichenoid dysplasia”, and “adverse effects of dental materials”. REVIEW RESULTS: OLLs seem to grossly underrated and most cases were clubbed as OLP. Definite clinical and histological features were uncovered to establish the identity of this lesion. Associations with dental restorative materials, drugs, and medications have been conclusively proven in the etiology of this condition. Specific markers are being utilized to diagnose the condition and monitor its progress. CONCLUSION: Substantial differentiating features were uncovered to delineate OLLs as a separate entity with definite etiology, pathogenesis, and a high malignant transformation rate compared with OLP. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4318020/ /pubmed/25657414 http://dx.doi.org/10.4103/0019-5154.147830 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | E-IJD Review Article Kamath, Venkatesh Vishwanath Setlur, Krishnanand Yerlagudda, Komali Oral Lichenoid Lesions - A Review and Update |
title | Oral Lichenoid Lesions - A Review and Update |
title_full | Oral Lichenoid Lesions - A Review and Update |
title_fullStr | Oral Lichenoid Lesions - A Review and Update |
title_full_unstemmed | Oral Lichenoid Lesions - A Review and Update |
title_short | Oral Lichenoid Lesions - A Review and Update |
title_sort | oral lichenoid lesions - a review and update |
topic | E-IJD Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318020/ https://www.ncbi.nlm.nih.gov/pubmed/25657414 http://dx.doi.org/10.4103/0019-5154.147830 |
work_keys_str_mv | AT kamathvenkateshvishwanath orallichenoidlesionsareviewandupdate AT setlurkrishnanand orallichenoidlesionsareviewandupdate AT yerlaguddakomali orallichenoidlesionsareviewandupdate |