The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)

A 13-year-old female child presented with bilateral proptosis and subconjuctival hemorrhage of 2 months duration. Subsequently, the biopsy and peripheral smears confirmed the diagnosis of acute myeloid leukemia (AML). Recurrent cytogenetic translocation t(8:21) in AML associated with extramedullary...

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Autores principales: Kapoor, Rohit, Khunger, Jitender Mohan, Sharma, Atul, Sachdeva, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318111/
https://www.ncbi.nlm.nih.gov/pubmed/25664277
http://dx.doi.org/10.4103/2229-516X.149256
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author Kapoor, Rohit
Khunger, Jitender Mohan
Sharma, Atul
Sachdeva, Soumya
author_facet Kapoor, Rohit
Khunger, Jitender Mohan
Sharma, Atul
Sachdeva, Soumya
author_sort Kapoor, Rohit
collection PubMed
description A 13-year-old female child presented with bilateral proptosis and subconjuctival hemorrhage of 2 months duration. Subsequently, the biopsy and peripheral smears confirmed the diagnosis of acute myeloid leukemia (AML). Recurrent cytogenetic translocation t(8:21) in AML associated with extramedullary manifestation; was discovered which is a rare event. Furthermore, myeloperoxidase negative blasts and periodic acid Schiff negative blasts in AML with t(8:21) is a very rare combination to the best of our knowledge.
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spelling pubmed-43181112015-02-06 The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21) Kapoor, Rohit Khunger, Jitender Mohan Sharma, Atul Sachdeva, Soumya Int J Appl Basic Med Res Case Report A 13-year-old female child presented with bilateral proptosis and subconjuctival hemorrhage of 2 months duration. Subsequently, the biopsy and peripheral smears confirmed the diagnosis of acute myeloid leukemia (AML). Recurrent cytogenetic translocation t(8:21) in AML associated with extramedullary manifestation; was discovered which is a rare event. Furthermore, myeloperoxidase negative blasts and periodic acid Schiff negative blasts in AML with t(8:21) is a very rare combination to the best of our knowledge. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4318111/ /pubmed/25664277 http://dx.doi.org/10.4103/2229-516X.149256 Text en Copyright: © International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kapoor, Rohit
Khunger, Jitender Mohan
Sharma, Atul
Sachdeva, Soumya
The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
title The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
title_full The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
title_fullStr The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
title_full_unstemmed The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
title_short The paradox of recurrent with rare: A rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
title_sort paradox of recurrent with rare: a rare case of bilateral proptosis and facial palsy in acute myeloid leukemia with recurrent cytogenetic translocation t(8:21)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318111/
https://www.ncbi.nlm.nih.gov/pubmed/25664277
http://dx.doi.org/10.4103/2229-516X.149256
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