Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study

BACKGROUND: Caveolin-1 (CAV1) may be upregulated by hypoxia and acts in a tumor-dependent manner. We investigated CAV1 in tongue squamous cell carcinoma (TSCC) and its association with clinical outcomes, and studied in vitro possible ways for CAV1 accumulation in the tumor microenvironment (TME). ME...

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Detalles Bibliográficos
Autores principales: Vered, Marilena, Lehtonen, Meri, Hotakainen, Lari, Pirilä, Emma, Teppo, Susanna, Nyberg, Pia, Sormunen, Raija, Zlotogorski-Hurvitz, Ayelet, Salo, Tuula, Dayan, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318139/
https://www.ncbi.nlm.nih.gov/pubmed/25633184
http://dx.doi.org/10.1186/s12885-015-1030-6

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