Addition of histamine to subcutaneously injected Plasmodium berghei sporozoites increases the parasite liver load and could facilitate whole-parasite vaccination

BACKGROUND: Whole-parasite immunization remains the benchmark in malaria vaccine development. A major bottleneck in the translation of whole-parasite immunization towards routine vaccination is the mode of administration, since high degrees of protection are currently only achieved by intravenous, a...

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Detalles Bibliográficos
Autores principales: Pfeil, Johannes, Heine, Jan F, Mueller, Ann-Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318155/
https://www.ncbi.nlm.nih.gov/pubmed/25627880
http://dx.doi.org/10.1186/s12936-015-0552-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318155/
https://www.ncbi.nlm.nih.gov/pubmed/25627880
http://dx.doi.org/10.1186/s12936-015-0552-3

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