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Open questions: seeking a holistic approach for mitochondrial research

In addition to their role as energy generators, mitochondria play critical and active roles in diverse signalling pathways, from immunity to cell survival and cell fate decisions. However, there remain many open questions and challenges as we work towards integrating this mighty organelle into estab...

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Detalles Bibliográficos
Autor principal: McBride, Heidi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318159/
https://www.ncbi.nlm.nih.gov/pubmed/25651813
http://dx.doi.org/10.1186/s12915-015-0120-x
Descripción
Sumario:In addition to their role as energy generators, mitochondria play critical and active roles in diverse signalling pathways, from immunity to cell survival and cell fate decisions. However, there remain many open questions and challenges as we work towards integrating this mighty organelle into established paradigms of cellular physiology.