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Open questions: seeking a holistic approach for mitochondrial research
In addition to their role as energy generators, mitochondria play critical and active roles in diverse signalling pathways, from immunity to cell survival and cell fate decisions. However, there remain many open questions and challenges as we work towards integrating this mighty organelle into estab...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318159/ https://www.ncbi.nlm.nih.gov/pubmed/25651813 http://dx.doi.org/10.1186/s12915-015-0120-x |
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author | McBride, Heidi M |
author_facet | McBride, Heidi M |
author_sort | McBride, Heidi M |
collection | PubMed |
description | In addition to their role as energy generators, mitochondria play critical and active roles in diverse signalling pathways, from immunity to cell survival and cell fate decisions. However, there remain many open questions and challenges as we work towards integrating this mighty organelle into established paradigms of cellular physiology. |
format | Online Article Text |
id | pubmed-4318159 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43181592015-02-06 Open questions: seeking a holistic approach for mitochondrial research McBride, Heidi M BMC Biol Comment In addition to their role as energy generators, mitochondria play critical and active roles in diverse signalling pathways, from immunity to cell survival and cell fate decisions. However, there remain many open questions and challenges as we work towards integrating this mighty organelle into established paradigms of cellular physiology. BioMed Central 2015-02-05 /pmc/articles/PMC4318159/ /pubmed/25651813 http://dx.doi.org/10.1186/s12915-015-0120-x Text en © McBride; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Comment McBride, Heidi M Open questions: seeking a holistic approach for mitochondrial research |
title | Open questions: seeking a holistic approach for mitochondrial research |
title_full | Open questions: seeking a holistic approach for mitochondrial research |
title_fullStr | Open questions: seeking a holistic approach for mitochondrial research |
title_full_unstemmed | Open questions: seeking a holistic approach for mitochondrial research |
title_short | Open questions: seeking a holistic approach for mitochondrial research |
title_sort | open questions: seeking a holistic approach for mitochondrial research |
topic | Comment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318159/ https://www.ncbi.nlm.nih.gov/pubmed/25651813 http://dx.doi.org/10.1186/s12915-015-0120-x |
work_keys_str_mv | AT mcbrideheidim openquestionsseekingaholisticapproachformitochondrialresearch |