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Development and Validation of a LC-MS/MS Method for the Simultaneous Estimation of Amlodipine and Valsartan in Human Plasma: Application to a Bioequivalence Study

A reliable, simple, and robust liquid chromatography-tandem mass spectro-metric (LC-MS/MS) method has been developed and validated that employs solid-phase extraction for the simultaneous estimation of amlodipine and valsartan in human K(3)EDTA plasma using amlodipine-d4 and valsartan-d9 as internal...

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Detalles Bibliográficos
Autores principales: Jangala, Hemanth, Vats, Poonam, Khuroo, Arshad Hussain, Monif, Tausif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientia Pharmaceutica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318187/
https://www.ncbi.nlm.nih.gov/pubmed/25853070
http://dx.doi.org/10.3797/scipharm.1402-11