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Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia
BACKGROUND: The lung epithelium constitutes the first barrier against invading pathogens and also a major surface potentially exposed to nanoparticles. In order to ensure and preserve lung epithelial barrier function, the alveolar compartment possesses local defence mechanisms that are able to contr...
Autores principales: | Delaval, Mathilde, Boland, Sonja, Solhonne, Brigitte, Nicola, Marie-Anne, Mornet, Stéphane, Baeza-Squiban, Armelle, Sallenave, Jean-Michel, Garcia-Verdugo, Ignacio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318199/ https://www.ncbi.nlm.nih.gov/pubmed/25605549 http://dx.doi.org/10.1186/s12989-014-0078-9 |
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