Cargando…

Efflux transporters in blood-brain interfaces of the developing brain

The cerebral microvessel endothelium forming the blood-brain barrier (BBB) and the epithelium of the choroid plexuses forming the blood-CSF barrier (BCSFB) operate as gatekeepers for the central nervous system. Exposure of the vulnerable developing brain to chemical insults can have dramatic consequ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strazielle, Nathalie, Ghersi-Egea, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318338/ https://www.ncbi.nlm.nih.gov/pubmed/25698917 http://dx.doi.org/10.3389/fnins.2015.00021

Ejemplares similares

Transport and Metabolism at Blood–Brain Interfaces and in Neural Cells: Relevance to Bilirubin-Induced Encephalopathy
por: Gazzin, Silvia, et al.
Publicado: (2012)

Blood-brain barrier dysfunction in disorders of the developing brain
por: Moretti, Raffaella, et al.
Publicado: (2015)

Prostaglandin E(2 )metabolism in rat brain: Role of the blood-brain interfaces
por: Alix, Eudeline, et al.
Publicado: (2008)

Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid Barrier
por: Strazielle, Nathalie, et al.
Publicado: (2016)

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide
por: Koehn, Liam M., et al.
Publicado: (2019)

T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium
por: Strazielle, Nathalie, et al.
Publicado: (2016)

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain
por: Schmitt, Charlotte, et al.
Publicado: (2012)

Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat
por: Blondel, Sandrine, et al.
Publicado: (2022)

Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation
por: Ghersi-Egea, Jean-François, et al.
Publicado: (2015)

Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by Bilirubin at the Blood-CSF and Blood-Brain Barriers in the Gunn Rat
por: Gazzin, Silvia, et al.
Publicado: (2011)

Purified IgG from aquaporin-4 neuromyelitis optica spectrum disorder patients alters blood-brain barrier permeability
por: Cobo-Calvo, Alvaro, et al.
Publicado: (2020)

N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain
por: Mottahedin, Amin, et al.
Publicado: (2020)

Proteoglycan 4 Reduces Neuroinflammation and Protects the Blood–Brain Barrier after Traumatic Brain Injury
por: Bennett, Marissa, et al.
Publicado: (2021)

Complexity and developmental changes in the expression pattern of claudins at the blood–CSF barrier
por: Kratzer, Ingrid, et al.
Publicado: (2012)

Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development
por: Møllgård, Kjeld, et al.
Publicado: (2017)

Mechanisms That Determine the Internal Environment of the Developing Brain: A Transcriptomic, Functional and Ultrastructural Approach
por: Liddelow, Shane A., et al.
Publicado: (2013)

Correction: Mechanisms That Determine the Internal Environment of the Developing Brain: A Transcriptomic, Functional and Ultrastructural Approach
por: Liddelow, Shane A., et al.
Publicado: (2016)

Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection
por: Kratzer, Ingrid, et al.
Publicado: (2013)

The legacy of Malcolm Beverley Segal (1937–2019) on the science and fields concerned with choroid plexus and cerebrospinal fluid physiology
por: Chodobski, Adam, et al.
Publicado: (2019)

Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study
por: Saunders, Norman R., et al.
Publicado: (2015)

[(11)C]Flumazenil brain uptake is influenced by the blood-brain barrier efflux transporter P-glycoprotein
por: Froklage, Femke E, et al.
Publicado: (2012)

Pharmacokinetics of Quinacrine Efflux from Mouse Brain via the P-glycoprotein Efflux Transporter
por: Ahn, Misol, et al.
Publicado: (2012)

Hypoxic Stress Induced by Hydralazine Leads to a Loss of Blood-Brain Barrier Integrity and an Increase in Efflux Transporter Activity
por: Chatard, Morgane, et al.
Publicado: (2016)

Efflux transporters in rat placenta and developing brain: transcriptomic and functional response to paracetamol
por: Koehn, L. M., et al.
Publicado: (2021)

The Drosophila blood-brain barrier: development and function of a glial endothelium
por: Limmer, Stefanie, et al.
Publicado: (2014)

Genetic Predictors of Antipsychotic Efflux Impairment via Blood-Brain Barrier: Role of Transport Proteins
por: Nasyrova, Regina F., et al.
Publicado: (2023)

Remote Ischaemic Preconditioning Accelerates Brain to Blood Glutamate Efflux via EAATs-mediated Transport
por: Končekova, Jana, et al.
Publicado: (2023)

The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher
por: Chodobski, Adam, et al.
Publicado: (2015)

Expression of Tight Junction and Drug Efflux Transporter Proteins in an in vitro Model of Human Blood–Brain Barrier
por: Cioni, Chiara, et al.
Publicado: (2012)

Barrier mechanisms in the Drosophila blood-brain barrier
por: Hindle, Samantha J., et al.
Publicado: (2014)

Dissecting gene expression at the blood-brain barrier
por: Huntley, Melanie A., et al.
Publicado: (2014)

Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transmembrane transporters
por: Richardson, Samantha J., et al.
Publicado: (2015)

Blocking of efflux transporters in rats improves translational validation of brain radioligands
por: Shalgunov, Vladimir, et al.
Publicado: (2020)

Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL
por: Panahi, Mahmod, et al.
Publicado: (2020)

Lipid Transport and Metabolism at the Blood-Brain Interface: Implications in Health and Disease
por: Pifferi, Fabien, et al.
Publicado: (2021)

Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood–Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery
por: Cui, Yunhai, et al.
Publicado: (2019)

ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas
por: Gomez-Zepeda, David, et al.
Publicado: (2019)

BBBomics-Human Blood Brain Barrier Transcriptomics Hub
por: Kalari, Krishna R., et al.
Publicado: (2016)

“You Shall Not Pass”—tight junctions of the blood brain barrier
por: Bauer, Hans-Christian, et al.
Publicado: (2014)

Outer brain barriers in rat and human development
por: Brøchner, Christian B., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2fbnrupe7g313s37dbjv04ghbs