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Peptide Amyloid Surface Display

[Image: see text] Homomeric self-assembly of peptides into amyloid fibers is a feature of many diseases. A central role has been suggested for the lateral fiber surface affecting gains of toxic function. To investigate this, a protein scaffold that presents a discrete, parallel β-sheet surface for a...

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Detalles Bibliográficos
Autores principales: Rubio, Marisa A., Schlamadinger, Diana E., White, Ellen M., Miranker, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318585/
https://www.ncbi.nlm.nih.gov/pubmed/25541905
http://dx.doi.org/10.1021/bi5011442