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Ring closure activates yeast γTuRC for species-specific microtubule nucleation

The γ-tubulin ring complex (γTuRC) is the primary microtubule nucleator in cells. γTuRC is assembled from repeating γ-tubulin small complex (γTuSC) subunits and is thought to function as a template by presenting a γ-tubulin ring that mimics microtubule geometry. However, a previous yeast γTuRC struc...

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Detalles Bibliográficos
Autores principales: Kollman, Justin M., Greenberg, Charles H., Li, Sam, Moritz, Michelle, Zelter, Alex, Fong, Kimberly K., Fernandez, Jose-Jesus, Sali, Andrej, Kilmartin, John, Davis, Trisha N., Agard, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318760/
https://www.ncbi.nlm.nih.gov/pubmed/25599398
http://dx.doi.org/10.1038/nsmb.2953