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11β-Hydroxysteroid Dehydrogenase Activity in the Brain Does Not Contribute to Systemic Interconversion of Cortisol and Cortisone in Healthy Men

CONTEXT AND OBJECTIVE: 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) catalyses regeneration of cortisol in liver, adipose tissue, and skeletal muscle, making a substantial contribution to circulating cortisol as demonstrated in humans by combining stable isotope tracer infusion with arteriovenou...

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Detalles Bibliográficos
Autores principales:	Kilgour, Alixe H.M., Semple, Scott, Marshall, Ian, Andrews, Peter, Andrew, Ruth, Walker, Brian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318893/ https://www.ncbi.nlm.nih.gov/pubmed/25393644 http://dx.doi.org/10.1210/jc.2014-3277

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