First evidence of Seoul hantavirus in the wild rat population in the Netherlands

We report the first detection of Seoul hantavirus (SEOV)-specific antibodies in the wild brown rat population in the Netherlands. SEOV-reactive antibodies were found in three rats out of 16 in a repeated series of tests including immunofluorescence assay, immunoblot, and enzyme-linked immunosorbent...

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Detalles Bibliográficos
Autores principales: Verner-Carlsson, Jenny, Lõhmus, Mare, Sundström, Karin, Strand, Tanja M., Verkerk, Monique, Reusken, Chantal, Yoshimatsu, Kumiko, Arikawa, Jiro, van de Goot, Frank, Lundkvist, Åke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318940/
https://www.ncbi.nlm.nih.gov/pubmed/25656468
http://dx.doi.org/10.3402/iee.v5.27215
Descripción
Sumario:We report the first detection of Seoul hantavirus (SEOV)-specific antibodies in the wild brown rat population in the Netherlands. SEOV-reactive antibodies were found in three rats out of 16 in a repeated series of tests including immunofluorescence assay, immunoblot, and enzyme-linked immunosorbent assay. Focus reduction neutralization test confirmed the presence of SEOV-specific antibodies, and reverse-transcription polymerase chain reaction (RT-PCR) confirmed the presence of hantaviral RNA. This discovery follows the recent findings of SEOV infections in wild and pet brown rats and humans in England, Wales, France, Belgium, and Sweden, indicating an even higher importance of this hantavirus for public health in large areas of Europe.

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