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Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein

Hedgehog proteins are secreted morphogens that play critical roles in development and disease. During maturation of the proteins through the secretory pathway, they are modified by the addition of N-terminal palmitic acid and C-terminal cholesterol moieties, both of which are critical for their corr...

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Detalles Bibliográficos
Autores principales:	Konitsiotis, Antonio D., Jovanović, Biljana, Ciepla, Paulina, Spitaler, Martin, Lanyon-Hogg, Thomas, Tate, Edward W., Magee, Anthony I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	Membrane Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319003/ https://www.ncbi.nlm.nih.gov/pubmed/25505265 http://dx.doi.org/10.1074/jbc.M114.614578

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