System-wide analysis of the transcriptional network of human myelomonocytic leukemia cells predicts attractor structure and phorbol-ester-induced differentiation and dedifferentiation transitions

We present a system-wide transcriptional network structure that controls cell types in the context of expression pattern transitions that correspond to cell type transitions. Co-expression based analyses uncovered a system-wide, ladder-like transcription factor cluster structure composed of nearly 1...

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Detalles Bibliográficos
Autores principales: Sakata, Katsumi, Ohyanagi, Hajime, Sato, Shinji, Nobori, Hiroya, Hayashi, Akiko, Ishii, Hideshi, Daub, Carsten O., Kawai, Jun, Suzuki, Harukazu, Saito, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319166/
https://www.ncbi.nlm.nih.gov/pubmed/25655563
http://dx.doi.org/10.1038/srep08283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319166/
https://www.ncbi.nlm.nih.gov/pubmed/25655563
http://dx.doi.org/10.1038/srep08283

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