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Macitentan: An important addition to the treatment of pulmonary arterial hypertension
Macitentan is an orphan drug for the treatment of pulmonary arterial hypertension (PAH). Endothelin-1 (ET-1) plays a critical role of pathophysiology of PAH. Macitentan, a new dual endothelin receptor antagonist, has reportedly improved prognosis of PAH patients by delaying the progression of diseas...
Autores principales: | Khadka, Anjan, Singh Brashier, Dick B, Tejus, Anantharamu, Sharma, Ashok Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319253/ https://www.ncbi.nlm.nih.gov/pubmed/25709357 http://dx.doi.org/10.4103/0976-500X.149151 |
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