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Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis

OBJECTIVE: The primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects. MATERIALS AND METHODS: Thirty-eight intr...

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Autores principales: Mathur, Ashish, Bains, Vivek Kumar, Gupta, Vivek, Jhingran, Rajesh, Singh, G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319284/
https://www.ncbi.nlm.nih.gov/pubmed/25713492
http://dx.doi.org/10.4103/1305-7456.149653
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author Mathur, Ashish
Bains, Vivek Kumar
Gupta, Vivek
Jhingran, Rajesh
Singh, G. P.
author_facet Mathur, Ashish
Bains, Vivek Kumar
Gupta, Vivek
Jhingran, Rajesh
Singh, G. P.
author_sort Mathur, Ashish
collection PubMed
description OBJECTIVE: The primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects. MATERIALS AND METHODS: Thirty-eight intrabony defects (IBDs) were treated with either open flap debridement (OFD) with PRF or OFD with ABG. Clinical parameters were recorded at baseline and 6 months postoperatively. The defect-fill and defect resolution at baseline and 6 months were calculated radiographically (intraoral periapical radiographs [IOPA] and orthopantomogram [OPG]). RESULTS: Significant probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, defect fill and defect resolution at both PRF and ABG treated sites with OFD was observed. However, inter-group comparison was non-significant (P > 0.05). The bivariate correlation results revealed that any of the two radiographic techniques (IOPA and OPG) can be used for analysis of the regenerative therapy in IBDs. CONCLUSION: The use of either PRF or ABG were effective in the treatment of three wall IBDs with an uneventful healing of the sites.
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spelling pubmed-43192842015-02-24 Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis Mathur, Ashish Bains, Vivek Kumar Gupta, Vivek Jhingran, Rajesh Singh, G. P. Eur J Dent Original Article OBJECTIVE: The primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects. MATERIALS AND METHODS: Thirty-eight intrabony defects (IBDs) were treated with either open flap debridement (OFD) with PRF or OFD with ABG. Clinical parameters were recorded at baseline and 6 months postoperatively. The defect-fill and defect resolution at baseline and 6 months were calculated radiographically (intraoral periapical radiographs [IOPA] and orthopantomogram [OPG]). RESULTS: Significant probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, defect fill and defect resolution at both PRF and ABG treated sites with OFD was observed. However, inter-group comparison was non-significant (P > 0.05). The bivariate correlation results revealed that any of the two radiographic techniques (IOPA and OPG) can be used for analysis of the regenerative therapy in IBDs. CONCLUSION: The use of either PRF or ABG were effective in the treatment of three wall IBDs with an uneventful healing of the sites. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4319284/ /pubmed/25713492 http://dx.doi.org/10.4103/1305-7456.149653 Text en Copyright: © European Journal of Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mathur, Ashish
Bains, Vivek Kumar
Gupta, Vivek
Jhingran, Rajesh
Singh, G. P.
Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis
title Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis
title_full Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis
title_fullStr Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis
title_full_unstemmed Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis
title_short Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis
title_sort evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: a comparative analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319284/
https://www.ncbi.nlm.nih.gov/pubmed/25713492
http://dx.doi.org/10.4103/1305-7456.149653
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